Prof Brian Johnstone is the Director of Orthopaedic Research at Oregon Health & Science University. Prof Johnstone conducted his pre-doctoral research at the Kennedy Institute of Rheumatology in London, England and postdoctoral studies at the University of North Carolina at Chapel Hill, USA. His work on intervertebral disc biology was acknowledged with two Volvo prizes. As a faculty member at Case Western Reserve University, he developed and patented the in vitro system for the chondrogenic induction of stem cells using ‘Photopolymerizable Semi-Interpenetrating Networks based on Poly (ethylene glycol)’. Prof Johnstone has served as President of the Orthopaedic Research Society and is currently the Director of Orthopaedic Research at Oregon Health & Science University, where he continues his work on basic and applied studies of stem cells in skeletal tissue repair and regeneration.